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M94A3026.TXT
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1994-10-25
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Document 3026
DOCN M94A3026
TI Epidemiologic approaches: AIDS related Kaposi's sarcoma (KS).
DT 9412
AU Haverkos HW; Drotman DP; NIH, Rockville, MD 20857.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):170 (abstract no. PB0106). Unique
Identifier : AIDSLINE ICA10/94369549
AB OBJECTIVE: We reviewed 12 epidemiologic studies conducted among gay men
with AIDS to examine the role of potential cofactors in the development
of KS. METHODS: Aspects of the studies reviewed include basic study
design, wording of the questionnaires (regarding nitrite inhalant use
provided by investigators), and published results comparing KS patients
with those who developed opportunistic infections indicative of AIDS.
The studies included questions about sociodemographics, medical history,
use of drugs, travel, and sexual behaviors. Patients were invited to
provide blood and/or other specimens for laboratory analysis. RESULTS:
The results of the epidemiologic studies are inconclusive. Nitrite
inhalant use was a variable often associated with KS (5 studies). The
differences in outcomes of these studies may reflect differences in
study designs, sample sizes, timing, quality, and content of interviews
regarding nitrites, sexual behaviors and other potential cofactors.
CONCLUSION: The etiology of KS is unknown. Epidemiologic study with
careful consideration to content of questionnaires and laboratory
testing may yet reveal the causes or cofactors for this tumor.
DE Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION
AIDS-Related Opportunistic Infections/EPIDEMIOLOGY/ETIOLOGY Causality
Human Male Nitrites Risk Factors Sarcoma,
Kaposi's/*EPIDEMIOLOGY/ETIOLOGY Sex Behavior Skin
Neoplasms/*EPIDEMIOLOGY/ETIOLOGY Substance Use
Disorders/COMPLICATIONS/EPIDEMIOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).